Browser Focus Generating Unsaved Changes Warning?

Our users seem to be having the "unsaved changes" warning messages pop up more in recent days/weeks. It seems like user interface is pretty "touchy" about leaving the focus during entry/editing (e.g. to take a call, look something else up in a different tag). 

Has anyone else noticed this? Are there any best practices for using SugarCRM on demand to minimize these types of messages?